A disturbance of the body’s acid/base balance in which there is accumulation or loss of alkali (base). There are two variations of acidosis namely metabolic and respiration.
In metabolic acidosis excess acid is made by metabolic processes. One type of metabolic acidosis is ketoacidosis, which happens in uncontrolled diabetes mellitus and starvation. Metabolic acidosis can also be caused by loss of bicarbonate (an alkali) due to heavy diarrhoea. In kidney failure insufficient acid is excreted in the urine.
When breathing fails to remove enough carbon dioxide from the lungs respiratory acidosis occurs. Chronic obstructive pulmonary disease can lead to respiratory acidosis from impaired breathing.